Lizzie McGuire (television) Half-hour series mixing live-action and animation on Disney Channel; premiering on January 19, 2001. The series covers the life of 13-year-old Lizzie McGuire as she stumbles into her adolescence with all its attendant crises and joys. Stars Hilary Duff (Lizzie McGuire), Hallie Todd (Jo McGuire), Robert Carradine (Sam McGuire), Jake Thomas (Matt McGuire). Working title was What’s Lizzie Thinking? The series began airing as part of ABC’s ABC Kids Saturday morning lineup on September 20, 2003.